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Some effects persist beyond active use

Several small observational studies and animal models suggest GLP-1 receptor activation in the hypothalamus may reduce CRH release, the upstream trigger for cortisol production

The five qualifying conditions The five qualifying conditions for the NHS pathway under NICE TA1026 are 4 : Type 2 diabetes High blood pressure (hypertension) Cardiovascular disease (previous heart attack, stroke, angina, or coronary procedure) High cholesterol or dyslipidaemia Obstructive sleep apnoea For the private route, the Mounjaro and Wegovy product licences accept any one of these, plus prediabetes (an HbA1c blood-sugar reading between 42 and 47 mmol/mol) 1,2

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That is why we ask you to bring a list of all drugs or medications you are taking or have taken in the past year to your appointment

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