Interestingly, exendin-4 is similar in structure and function to GLP-1, but is resistant to degradation by DPP4, allowing exendin-4 to remain in circulation for hours rather than just a few minutes
The interview schedule was developed through discussion with healthcare professionals including a clinician working in a tier 3 obesity service, a diabetes physician, and a psychiatrist specialising in diabetes and mental health, as well as a member of the public with lived experience of taking a GLP-1 receptor agonist (see supplementary material p3)
Post-operatively, discomfort is typically mild and well managed with paracetamol
If weight increases by more than 5 percent or appetite becomes difficult to manage, return to the previous higher dose
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