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Molecular Basis of G6PD Deficiency In principle, genetically determined deficiency of G6PD, like that of any other protein, might be attributed either to quantitative changes, such as mutations that affect the amount of the enzyme but not its structure, or to qualitative changes, such as mutations that affect the structure of the enzyme and hence its stability or catalytic efficiency

[PubMed ID: 28093794]

Loss of Kmt2c in vivo leads to EMT, mitochondrial dysfunction and improved response to lapatinib in breast cancer

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