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Additionally, many POTS patients rely on caffeine to constrict blood vessels and improve cerebral blood flow, but struggle with caffeine-induced tachycardia and jitters

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For some, this means melatonin helps get them to sleep but is not so helpful in keeping them asleep

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Annu Rev Pharmacol Toxicol 45:5188 Huang KP, Huang FL (2002) Glutathionylation of proteins by glutathione disulfide S -oxide

Developing novel experimental models and analytical techniques in laboratory settings may also provide new opportunities for investigating the blend's properties and mechanisms