This leads to a reduction in TCA cycle gene expression and oxygen consumption as well as an increase in lactate production and cell proliferation 89
Potential Negative Effects on Mental Health While the potential benefits are encouraging, its crucial to acknowledge the potential negative impacts of GLP-1 inhibitors on mental health: Increased Anxiety and Agitation: Paradoxically, while some studies suggest anxiety reduction, others have reported instances of increased anxiety, restlessness, and agitation in individuals taking GLP-1 agonists
The drug is in later-stage clinical trials, with phase 3 trials underway to determine broader efficacy and safety
Nerve pain, or neuropathic pain, associated with vitamin B12 deficiency typically manifests as tingling, numbness, burning sensations, or sharp pains in the hands and feet
For ongoing nutritional support, the GLP-1 Daily Support supplement may also be a helpful fit
The "energy food" approach When appetite is suppressed and you can only eat small amounts, choosing the right foods becomes disproportionately important