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Withdrawal symptoms are treated safely through medication-assisted treatment (MAT), medical monitoring, supportive care, and behavioral interventions

51% of patients responded equally to hydroquinone and kojic acid 28% of patients saw a more dramatic reduction in pigment on the kojic acid side 21% had a more dramatic improvement with the hydroquinone cream Said that, Hydroquinone was found to work faster than Kojic Acid

doi: 10.1177/0269881113508830 62 GillbergC.BillstedtE

These include liver and kidney stress, immune suppression with repeated use of high-dose glutathione, and the potential risk of cancer

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The subjects were randomized to receive glutathione capsules in a dose of 500 mg/day in two divided doses, or placebo for four weeks