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70 They neutralize free radicals directly and regenerate other antioxidants

Increased GH-release: K Raun et al

Diabetes Res Clin Pract 170:108532

They might also get a bit of diarrhea or itchiness

Author Contributions Jos Luis Grriz provided expert clinical opinion and critical revision of the manuscript for important intellectual content and has helped establish the structure and contents of the manuscript

Situations requiring healthcare provider consultation: Frequent dose timing inconsistencies that suggest adherence challenges Concurrent illness affecting medication absorption or tolerance Addition of new medications that may interact with tirzepatide Persistent or worsening gastrointestinal symptoms Any uncertainty about appropriate dose timing Patients should be aware that tirzepatide may reduce the effectiveness of oral hormonal contraceptives due to delayed gastric emptying