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Diet and exercise is still first line but when it fails, GLP-1 receptor agonists offer a medically supported solution

10.1038/s41591-018-0222-4 111 SundelinE.GormsenL

injections (2 mg kg 1 ) formulated at 1 mg mL 1 in PBS 1

Progressive improvements in insulin sensitivity and metabolic health may facilitate ongoing fat mobilization even as total body weight decreases

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