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Comparative Biochemistry & Physiology Part A Molecular & Integrative Physiology 170 , 3845 (2014)

Glycocalyx degradation usually begins in the SIRS stage, when proinflammatory factors (TNF-, IL-1) activate endothelial cells and directly destroy the components of the glycocalyx (such as HS, HA) by activating MMPs [23]

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At the start of the experiment, mice were randomized to three different groups (1) AL, ad libitum diet

Another bonus is muscle protection