Ipamorelin + CJC-1295 Stack: Evidence, Mechanism, and Protocol At a glance Drug class / Growth hormone secretagogue (GHRP) + Growth hormone-releasing hormone analogue (GHRH analogue) Ipamorelin receptor target / Ghrelin receptor (GHSR-1a), selective, no cortisol or prolactin spike CJC-1295 receptor target / GHRH receptor (GHRHR) on pituitary somatotrophs Combination mechanism / GHRP + GHRH co-stimulation raises GH pulse amplitude 2-to-10-fold over either agent alone in animal models Typical ipamorelin dose / 100-300 mcg subcutaneous injection, 1-3x daily Typical CJC-1295 (no DAC) dose / 100-300 mcg subcutaneous injection, timed with ipamorelin Typical CJC-1295 with DAC dose / 1,000-2,000 mcg subcutaneous injection, once weekly Primary evidence level / Mechanistic + animal + one Phase II RCT (CJC-1295)
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The 16/8 method, which involves time restricted eating by fasting for 16 hours and eating within an 8-hour window, aligns well with natural overnight fasting and is convenient for many during the fasting period
For instance, studies have shown that applying IGF-1 to injured tendons in animal models accelerates the healing process, reduces scarring, and improves the mechanical properties of the healed tendons
Ipamorelin works by mimicking ghrelin, a hormone that is naturally produced by the enteroendocrine cells of the gastrointestinal tract [4]
IUPAC [(2R)-3-carboxy-2-propanoyloxypropyl]-dimethyl-(trideuteriomethyl)azanium;chloride Unlabelled CAS Number 119793-66-7 Product Data Shipping Temperature Room Temperature Product Type Stable Isotope Labelled Purity 99 atom % D, min 98% Chemical Purity