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Table 1 Published animal and human researches on the impact of GLP-1 on bone metabolism

Here are some key findings that support its mechanism of action

In foundational research, GLP-1 secretion was significantly blunted in animals lacking the FFAR2 receptor, pinning down the mechanism directly

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PMID: 10827002

3 Table 2 highlights the results of the use of GLP-1 RAs in treating HS from multiple case reports, a prospective proof-of-concept study, and a retrospective cohort study