delayed injection site reaction tirzepatide Treatment: Evidence-Based Management Guide What is the likely cause

Dehydration may also occur following bouts of vomiting or diarrhea

Severe or persistent injection site reactions leading to treatment discontinuation are uncommon in clinical trials

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Cardiovascular risk factors included mean low-density lipoprotein cholesterol (LDL-C) of approximately 80 mg/dL, systolic BP of 135 mm Hg, and mean estimated glomerular filtration rate (eGFR) of 79 mL/min/1.73 m, with 23% classified as Kidney Disease Improving Global Outcomes (KDIGO) high or veryhighrisk chronic kidney disease (CKD)

Patel et al

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