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GLP-1 drugs like Ozempic and Mounjaro have helped many people lose weight and manage type 2 diabetes, but a big question remains: what happens when people stop using them

This is one reason sports medicine clinicians pay close attention to concepts like Relative Energy Deficiency in Sport (RED-S)

Rybelsus is an oral GLP-1 thats approved for type 2 diabetes and contains semalgutide as its active ingredient

The pharmaceutical design priorities emphasized efficacy with minimal liver toxicity and no aromatization to estrogen

For example, GLP-1RAs can target invariant natural killer T (iNKT) cells and consequently reduce the production of proinflammatory cytokines such as IFN-, IL-2, IL-4, IL-10, IL-17, TNF-, and GM-CSF and possibly increase the production of anti-inflammatory cytokines such as IL-10

Cyanocobalamin is included at a concentration of 0.5 mg/mL across all available strengths