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This modulation is tentatively evidenced by a reported decrease in the expression of pro-inflammatory cytokines such as tumor necrosis factor-alpha (TNF-), interferon-gamma (IFN-), interleukin-1 beta (IL-1), and transforming growth factor-beta (TGF-), alongside chemokines like CCL2, CCL5, and CXCR4 following MGF experimentation

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demonstrated that activation of microglia through the AHR pathway upregulates pro-inflammatory molecules, such as tumor growth factor- (TGF-) and vascular endothelial growth factor B (VEGF-B)

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