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Peptides A6A8 carrying charges of +5, +4, and +3 respectively, which are obtained by the substitution of Lys4, Lys4Arg11, or Lys4Arg6Arg11 of A4 with L -alanine, showed gradually decreasing cell penetration ability compared with A4 with +6 positive charges (Figure 11C)

Medical history: Health conditions, pregnancy, breastfeeding, recent illness, and prior reactions are reviewed first

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