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Until then, PAs for weight-loss indications are ending and expire Dec 31, 2025
Semaglutide has phase 2 data (Newsome 2021 NEJM) showing about 59% MASH resolution at 72 weeks
Some folks also dig alternative and complementary therapies like yoga, behavioral therapy, acupuncture, or massage therapy.
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[26] showed that liraglutide-dependent weight loss relies on its binding to GLP-1Rs located mainly in POMC/CART (cocaine- and amphetamine-regulated transcript) anorexigenic neurons in the ARC, but an indirect inhibitory effect of agouti-related peptide (AgRP) orexigenic neurons via -aminobutyric acid (GABA)-ergic signaling was also observed
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