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10.1152/ajprenal.1985.249.1.F1 Am

If the skins collagen and elastin fibers aren't robust enough to bounce back, you may notice fine lines, wrinkles, and a lack of firmness

The remaining mature cell types include mucin-producing goblet cells, antimicrobial defensins-producing Paneth cells, peptide-hormone-producing enteroendocrine cells, and cytokine-producing tuft cells which reside throughout the epithelium (Ensari and Marsh, 2018)

The samples were centrifuged at 16,600 g for 10 min at 4C