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Millions of people are living with arthritis, stuck in a cycle of temporary relief and long-term damage

Phospholipid hydroperoxide glutathione peroxidase (GPX4) Essential antioxidant peroxidase that directly reduces phospholipid hydroperoxide even if they are incorporated in membranes and lipoproteins (By similarity)

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In contrast to IL-10, tumor necrosis factor induced protein 3 (TNFAIP3), also known as an anti-inflammatory protein (43), was already downregulated at 24 h and reached again the initial level at 14 d pi

We analyze molecular mechanisms, evaluate clinical evidence, and discuss practical applications while identifying key research priorities for clinical translation

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