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Furthermore, TFS can increase drug deposition in the skin and extend the duration of effective drug concentrations, reducing the frequency of administration (165)

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However, since the tubular reabsorption occurs via an active transporter, once the transporter is saturated by the high plasma L-carnitine concentrations achieved by intravenous administration, the circulating L-carnitine is rapidly excreted

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Tom20 senses iron-activated ROS signaling to promote melanoma cell pyroptosis