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Additionally, pressurized liquid extraction involves the application of elevated temperatures and pressures, which can potentially lead to the degradation of thermolabile polyphenolic compounds, thereby reducing the yield and altering the composition of the extracts (77)

3 Pharmacological effects Studies on Scrophulariae Radix have highlighted its anti-inflammatory, antioxidant, immunomodulatory, cardiovascular protective, and antitumor effects ( 3.1 Anti-inflammatory effects Key components of Scrophulariae Radix , including iridoid glycosides such as aucubin and geniposide, show strong anti-inflammatory activity (84)

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Elevated prefrontal GABA levels were significantly associated with reduced prefrontal CBF (Fig

Reports suggest that l-glutathione may help reduce the symptoms and enhance patients' quality of life with Parkinson's

Managing Side Effects The combination is generally well tolerated, but most patients experience at least mild side effects in the first 8 weeks