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If one causes intolerable side effects, trying the other is reasonable

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"Analytical approaches for the detection of emerging therapeutics and non-approved drugs in human doping controls." Journal of pharmaceutical and biomedical analysis 101 (2014): 66-83

NNMT upregulation was documented to elevate homocysteine levels, activating pro-inflammatory and pro-oxidative cascades including TLR4-NF-B and STAT3-IL-1 signalling

discomfort or pain at the injection site