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To date, there has been seven human coronaviruses (HCoVs) identified: severe acute respiratory syndrome coronavirus (SARS-CoV-2), SARS-CoV, Middle East respiratory syndrome coronavirus (MERS-CoV), Human coronavirus 229E (HCoV-229E), HCoV-OC43, HCoV-NL63, and HKU-1

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H 2 S n sulfurate cysteine residues of Keap1 to release Nrf2 from Keap1/Nrf2 complex to the nucleus where Nrf2 upregulates the transcription of antioxidant genes, resulting in the increase in GSH production 23