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Clinical Monitoring May Be Required: Patients with fluid retention or renal impairment , such as those with congestive heart failure or pulmonary edema Electrolyte and acid-base balance should be monitored during administration May interact with some medications (e.g., corticosteroids, corticotropin) Important Note: Sodium Chloride Injection must be used once and discarded

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Finally, electrophilic diazenium diolates were designed as prodrugs for spontaneous nitric oxide (NO) release at physiological pH, after a reaction with GSH catalyzed by GST