22(5): p
To enhance sensitivity, specificity, and translational relevance, future research should incorporate multimodal biomarker strategiescombining imaging, fluid-based, and multi-omics analyses
Since our proteomic study suggested mitochondrial alterations following HC treatment, and considering the recent hypothesis of Simeone (Simeone, 2025) that HC might interact with key cellular antioxidant systems, mitochondrial function was further investigated through oxygen consumption rate (OCR), extracellular acidification rate (ECAR), mitochondrial membrane potential, mitochondrial network morphology, ROS production and GSH/GSSG ratio
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These factors can have an adverse effect on physiological and biochemical metabolism and can ultimately inhibit plant growth, or even lead to death [5,6,7]
Kiricuta I, Willner J, Kolbl O
