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Electrophysiology Neurons were constantly perfused at 3 ml min 1 with heated (3032 C), gassed (95% O 2 , 5% CO 2 ) artificial cerebrospinal fluid (pH 7.4, 300305 mOsm) containing (in mM): 119 NaCl, 2.5 KCl, 1.3 MgCl 2 , 2.5 CaCl 2 , 26 NaHCO 3 , 1.3 NaH 2 PO 4 , 20 D-glucose and 0.5 sodium ascorbate

In addition, during vaso-occlusive episodes, SCD patients show distinct metabolite profiles from those at steady-state 7,8,9,10

M.RahmanA.HasanuzzamanM.NaharK.FujitaM

In recent years, there has been a marked increase in the registration of global clinical trials examining CAR-T therapies for SLE, with clinicaltrials.gov indicating over 30 registered trials ( Taken together, this review aims to evaluate the potential of CAR-T cell therapy in treating SLE\-related diseases