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doi:10.1146/annurev.nutr.24.012003.132418

The antioxidant effect of GPX4 depends on the presence of GSH as a reducing agent, with two GSH reducing one LOOH

The deletion of Dnmt1 in excitatory neurons of the dorsal forebrain in mice, although these mice are viable into adulthood, results in hypomethylation, dysregulation of gene expression, defects in dendritic branching, and progressive apoptotic degeneration of dorsal forebrain [74]

Cys151 residue is required to inhibit Keap1-mediated Nrf2 degradation, thus itaconate upregulates Nrf2 levels via Keap1 alkylation ( Figure 3 )

Funding This work has been supported by the Minister of Education and Science in Poland as part of the program Student Scientific Groups Create Innovations (Grant No

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