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Burrows TL, Martin RJ, Collins CE

This small peptide is eliminated by the kidneys and has a plasma half-life of approximately 3 hours, requiring twice-daily subcutaneous injections

Hence, CCK receptors (CCKRs) regulate a variety of physiological functions including digestion, satiety, emotion regulation, pain sensation, and memory process 18,19,20,21,22,23,24,25

2025 Nov 25:259:115314

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While acknowledging the strengths of the study, such as participant criteria, low drop-out rates and high adherence, the researchers also acknowledged limitations, including the relatively short intervention duration and the absence of a third intervention group receiving synbiotics alongside a placebo