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Hydroxytrimethyllysine Aldolase (HTMLA) The next step involves the cleavage of HTML by HTMLA, a cytosolic enzyme that splits the molecule into 4-trimethylaminobutyraldehyde (TMABA) and glycine

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(13) These findings suggest a promising osteogenic role for GLP-1 therapies, especially in metabolic disease contexts

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Wet beriberi In addition to neurologic symptoms, wet (cardiac) beriberi is characterized by cardiovascular manifestations of thiamin deficiency, which include rapid heart rate, enlargement of the heart, severe swelling (edema), difficulty breathing, and ultimately, congestive heart failure

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