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GHK-Cu interacts with both phases, but not equally

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These genes include PCK1, which encodes the cytosolic form of phosphoenolpyruvate carboxykinase (PEPCK), and G6PC1, which encodes glucose-6-phosphatase

Women with a history of copper sensitivity or who take high-dose zinc supplements (which compete with copper absorption) should track copper status if using injectable GHK-Cu for extended periods