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Protein degradation is a complicated post-translational process in cells

Loss of IFN- can therefore dampen the ability of the host immune system to control intracellular infections

Endothelial dysfunction or death can precipitate various pathological conditions, including vascular barrier disruption and vasoconstrictive/vasodilatory dysfunction

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This difference alone explains why dermatology is shifting toward gentler, sustainable brightening agents

Distinct proteomic and post-translational impacts of class-defining AML alterations To explore the imprint of recurrent genetic alterations on the AML proteome, we linked common genetic alterations to differences in the abundance of proteins and PTMs (Methods)