Glutathione is a key antioxidant in the brain, as it is the first line of defence in protecting against reactive oxygen species, which are cellular by-products that can lead to cellular damage, oxidative stress, and DNA damage
Our mitochondriathe cells energy production centersare dependent on glutathione, which can cross mitochondrial membranes and minimize reactive oxygen species (ROS) buildup
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Sonsalla PK, Zeevalk GD, German DC
Organic anion transporter 3 mediates the efflux transport of an amphipathic organic anion, dehydroepiandrosterone sulfate, across the blood-brain barrier in mice
This is the central scientific question, and the answer is: possibly in some experimental systems, but the evidence base is still narrow