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Conclusion In conclusion, this study establishes a comprehensive forensic biomarker profile for GLP toxicity, characterized by hematological suppression, significant thyroid hormone disruption (elevated TSH, suppressed T3/T4), elevated oxidative stress (increased MDA, decreased SOD), and the induction of apoptotic signaling (downregulated Bcl-2, upregulated Bax and Caspase-3)

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doi: 10.1210/en.2011-2170 18 BaggioLLDruckerDJ