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NICE recommends: Consider SLNB for melanoma with a Breslow thickness of 0.8 mm to 1.0 mm with ulceration, lymphovascular invasion or a mitotic index of 2 or more Consider SLNB for melanoma with a Breslow thickness greater than 1.0 mm SLNB is typically performed after diagnostic excision, often at the time of wide local excision in suitable patients

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