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[1] Body weight and composition can influence the volume of distribution for GLP-1 medications, potentially affecting elimination kinetics

Hair loss occurs in a subset of patients, typically related to rapid weight loss rather than the medication directly

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Details on the isolation of mouse caSMCs and neonatal ventricular CMs, as well as cell culture methods for human caSMCs, caECs, hESC-CMs, and the HL-1 cell line, including drug treatment regimens, are provided in the Supplemental Methods

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