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(95) found that the application of MEL in laboratory animals with liver damage after CsA, reduced the activity of histological lesions and increased hepatocellular glutathione, MDA, and increased the activity of superoxide dismutase and catalase

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Up-regulating of miRNAs like miR-126-3p, miR-223-3p, miR-142-3p, as well as factors like indoleamine 2,3 dioxygenase (IDO), IL-10, prostaglandin E2 (PGE 2 ), hepatocyte growth factor (HGF), TGF-, heme oxygenase1 (HO-1), nitric oxide (NO), chemokine (CC motif) ligand 2 (CCL2), contribute to immunomodulation and anti-inflammatory function

No- 10016026000919 (FSSAI)

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