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ELX- 02, a novel aminoglycoside analog, avoided serious adverse events in preclinical models [155] and Phase 1 clinical trials [156]

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Research protocols that extend a single vial beyond 28 days risk administering biologically inert compound, rendering later doses ineffective without any indication that potency has collapsed

The SURMOUNT-4 trial demonstrated that participants who discontinued tirzepatide after initial weight loss regained approximately 14% of their body weight over 52 weeks, compared to those who continued treatment

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