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doi:10.1111/j.1600-0781.2011.00557.x

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94 Naive embryonic stem cells, such as those primed by NAD, also consume glutamine as an important nutrient and produce a-ketoglutarate for H3K27me3 demethylation, thereby maintaining the hypomethylated state of embryonic stem cells

A metaregression analysis of published data from 20 studies of 95,783 individuals followed for 12.4 years