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This makes it relevant to laboratory investigations involving receptor cross-talk, metabolic adaptation, glucose-associated signaling, appetite-associated pathway biology, energy expenditure models, substrate utilization, hepatic metabolic signaling, and adipose-associated response systems

If anything, protein needs increase slightly as appetite returns and caloric intake rises

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A study in 2014 found that cirrhotic patients on sodium-restricted diets consumed approximately 20% fewer calories than those without restriction, with no significant differences in serum sodium levels between groups [64]