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Studies generally report a weight loss of about 15-16% of initial body weight with Semaglutide, while Tirzepatide can result in a 14-18% reduction

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Biochimica et Biophysica Acta (BBA) 1842:12401247 Wong HS, Dighe PA, Mezera V, Monternier PA, Brand MD (2017) Production of superoxide and hydrogen peroxide from specific mitochondrial sites under different bioenergetic conditions

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10.4103/0253-7613.129321 63 MaiersJ