In vivo studies showed that PEGylated versions of these aptamers, administered intravenously, significantly reduced tumor Weight, by as Much as 91%, and lowered metastasis rates in orthotopic ovarian cancer mouse models
Hangartner, L
Therefore, different configurations of CTR and RAMP within the complex might dictate the activation of one or more of the various intracellular pathways, leading to the expression of the physiological effects
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This study was approved by the appropriate ethical committees indicated above CPP and CNIL (Biological Research & Collection BRC Identification number: 2020-A00478-31)
2013 Jun 1;1(2):128-132
