The analysts said a group of patients who eventually received the lowest maximum dose of the pill 90 milligrams still saw high rates of nausea "with limited weight loss efficacy." Another group of patients who took the highest maximum dose of the drug 120 milligrams with slightly lower dose increases over time had nausea rates of 83%, vomiting of 33% and diarrhea of 50%, according to the JPMorgan analysts
Participants were adults aged 18 years of age or older with either a body mass index (BMI) of 30 kg/m 2 or a BMI of 27 kg/m 2 with at least one or more weight-related comorbidities of the following: known CVD, hypertension, dyslipidemia, or obstructive sleep apnea (as defined below)
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Approximately 50% of ingested TMAO is absorbed unchanged and then excreted in urine
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was quite helpful in the entire learning process