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The four isotopic iTRAQ-labelled samples were combined and fractionated on a Waters ultra-performance LC instrument using a C18 column (Waters BEH C 18 2.1 50 mm, 1.7 m)

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Studies are lacking on the safety and efficacy of GLP-agonists in decompensated NASH cirrhosis

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Activation of the PI3K/AKT pathway primarily drives synapse formation and density increases, while MAPK/ERK pathway activation predominantly influences dendritic growth and arborization