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A hypervascular enlarged gland is seen in Graves disease, nodules in toxic multinodular goiter, and decreased Doppler flow in thyroiditis or factitious thyrotoxicosis

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Neutrophil-derived proteolytic enzymes (i.e., myeloperoxidase and elastase) may also be involved in the initiation of AT inflammation (132)

While they acknowledged a higher dose of IGF-1 LR3 may have yielded data to support the hypothesis, future investigations should consider potential associations with increased fetal demise observed in this study