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In turn, these free radicals cause further mitochondrial damage and so create a vicious cycle of less energy and more damage

Mechanism of time-dependent inhibition of 5 alpha-reductase by delta 1-4-azasteroids: Toward perfection of rates of time-dependent inhibition by using ligand-binding energies.Biochemistry1995;34:13453-3459 85

It does so by binding to harmful substances and facilitating their elimination

However, longer isn't always better

Role of glutathione S-transferases in the spinocerebellar ataxia type 2 clinical phenotype

complementarity determining regions (CDRs - CDR1, CDR2, CDR3) compared to 6 in classical antibodies, but still bind with affinities in nano/pico molar concentrations (177)