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Due to the rapid metabolism of lidocaine HCl, any condition affecting liver function may alter its kinetics, which can double the half-life in patients with liver dysfunction

J Rheumatol

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We applied this workflow for each of two distinct alkyne-modified probes per SCLA compound across both non-senescent and senescent (etoposide- or tozasertib-induced) SK-MEL-103 cells

Kodde IF, van der Stok J, Smolenski RT, de Jong JW (2007) Metabolic and genetic regulation of cardiac energy substrate preference