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Perinatal exposure of rodents to NP induced adipocyte differentiation, increased pparg expression, promoted the augmentation of body weight, accumulation of fat mass, and the increase of fasting serum glucose and total cholesterol levels in the offspring [226, 227]

4 Associated with cerebral ammonia accumulation is cytotoxic brain edema and the development of Alzheimers Type II astrocytes in the basal ganglia of HE patients

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doi: 10.1016/j.advnut.2024.100265