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Efforts have focused on GLP1RAs as a therapeutic option for T2DM since they inhibit appetite and food intake and improve glucose regulation

That trial, called SURPASS-CVOT, will finish in mid-2025 and could really give us the details we need to see how effective tirzepatide is in reducing heart disease, he says

Understanding the differences between them is essential for making an informed choice, since the medication you select directly affects your cost, results timeline, and side effect experience

However, researchers have compared the impact of both drugs from different studies and suggested that the higher doses (10mg and 15mg) of tirzepatide might reduce weight by 5.15kg more than 2mg of semaglutide