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Preclinical evidence supports the role of GLP-1RAs in alleviating neuropathic pain through the modulation of microglial activity, inflammatory cytokine production and -endorphin release [63, 65, 68, 70,71,72,73,74]

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[DOI] [PMC free article] [PubMed] [Google Scholar] 118.Puupponen-Pimi R., Nohynek L., Hartmann-Schmidlin S., Khknen M., Heinonen M., Mtt-Riihinen K., Oksman-Caldentey K.M

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Dipeptidyl peptidase IV resistant analogues of glucagon-like peptide-1 which have extended metabolic stability and improved biological activity