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October 1, 2024

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Molecular Weight: 1,419.53 DA

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GLP-1Rs are distributed widely throughout the body in humans and model organisms, with particular density in the pancreas -cells, gastrointestinal tract, brain, kidneys, heart, and blood vessels of other organs [17, 18]

On the other hand, l-carnitine, primarily sourced from red meat, is obtained exogenously through dietary intake 28 .Dietary l-carnitine is metabolized in humans in a gut microbiota-dependent manner to form -butyrobetaine (GBB), which is subsequently converted into trimethylamine (TMA), a precursor of trimethylamine N-oxide (TMAO) 29