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Serotonin, dopamine, GABA, and glutamate all respond to GLP-1 receptor activation

It sounds a cautionary note for short-term use without a more comprehensive approach to weight management.' Image source: West S, Scragg J, Aveyard P et al., The BMJ 2026 (CC BY 4.0) The Oxford team systematically reviewed 37 studies tracking more than 9,000 adults who stopped taking weight management medicines after being on them for an average of 39 weeks of treatment

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Additionally, semaglutide slows gastric emptying, promoting a feeling of fullness and assisting with weight management